Honduras was home to several important Mesoamerican cultures, most notably the Maya, prior to being conquered by Spain in the sixteenth century. The Spanish introduced Roman Catholicism and the now predominant Spanish language, along with numerous customs that have blended with the indigenous culture. Honduras became independent in 1821 and has since been a republic, although it has consistently endured much social strife and political instability, remaining one of the poorest countries in the Western Hemisphere. Honduras has the highest murder rate in the world.